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Question

Posted on: December 13 2016

Question by Dermatologe: Salicylic acid 10% in Efudix: Does the cream remain stable? Do the active ingredients remain stable?

Otherwise, she would switch to Verrumal

Answer

div class = "Gmail_default" style = "color: rgb (34, 34, 34); font-size: 13.6 px; font-family: Tahoma, sans-serif;" > In a previous reply, the discoloration was attributed to a reaction of salicylic acid with e.g. Fe ions and therefore the proposal EDTA Insert. You ask yourself questions about the stability of the active ingredient.   But 5-fluouracil is quite stable in acidic solutions = salicylic acid; and is very little soluble in water. So.............................. wbr/>.......... div class = "Gmail_default" style = "color: rgb (34, 34, 34); font-size: 13.6 px; font-family: Tahoma, sans-serif;" >   div class = "Gmail_default" style = "color: rgb (34, 34, 34); font-size: 13.6 px; font-family: Tahoma, sans-serif;" > Verrumal also contains 5-fluouracil but I can say if the doctor wants to switch to Verrumal with addition of salicylic acid, Try and see if there is any discoloration whatsoever. One never knows.   div class = "Gmail_default" style = "color: rgb (34, 34, 34); font-size: 13.6 px; font-family: Tahoma, sans-serif;" >   div class = "Gmail_default" style = "color: rgb (34, 34, 34); font-size: 13.6 px; font-family: Tahoma, sans-serif;" >