Question
Posted on: March 20 2016Elocom Lotion 20ml, Liq carb 10g, salicylic acid 5g in Isopropanol 30degree AD 100ml
Isopropanol 30 degrees, is the same formula used for this of alcohol?
Salicylic acid in isopropanol is clear, but becomes cloudy when adding Elocom
Answer
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span style = "FONT-size: 11.000000 pt; font-family: ' TimesNewRomanPS '; font-weight: 700" > What contains Elocom
P style = "line-height: 20.8 px;" > span style = "FONT-size: 11pt; font-family: TimesNewRomanPS; font-style: italic;" > 0.1% solution for cutaneous use: span style = "line-height: 1.6 em; font-size: 12pt; font-family: TimesNewRomanPSMT;" >- span style = "line-height: 1.6 em; font-size: 11pt; font-family: TimesNewRomanPSMT;" > The active ingredient is mometasonfuroate 1 mg/g. P style = "line-height: 20.8 px;" > span style = "line-height: 1.6 em; font-size: 11pt; font-family: TimesNewRomanPSMT;" >-the other ingredients are: span style = "FONT-family: TimesNewRomanPSMT; font-size: 11pt; line-height: 1.6 em;" > Isopropyl alcohol, hydroxypropylcellulose, propylene glycol, sodium dihydrogeenphosphate dihydrate, diluted phosphoric acid, purified water. P style = "line-height: 20.8 px;" > span style = "FONT-family: TimesNewRomanPSMT; font-size: 11pt; line-height: 1.6 em;" > considering you have this Elocom lotion further diluted with isopropanol of 30 degrees, in which you think salicylic acid is soluble, I suspect that mometasonfumarate precipitates. You should increase the isopropanol degree. You can rely on corticosteroid lotions, which are described in the TMF. I suspect that the composition of Elocom solution is similar.